English 
     
   首页
学院新闻
通知公告
学工动态
教育专栏
科研动态
下载中心       
友情链接
   热点信息
专业介绍
联系我们
学生工作办公室简介
招生问答
纳米科学技术学院2012年招生宣传片
语言中心主任致辞
我院近期科研成果被国际学术媒体报道
培养方案
刘庄教授课题组在Angewandte Chemie International Edition上发表论文
发布时间:2017-9-13 22:15:36 点击:

题目:

Degradable Vanadium Disulfide Nanostructures with Unique Optical and Magnetic Functions for Cancer Theranostics


作者:

Yuyan Chen, Liang Cheng,* Ziliang Dong, Yu Chao, Huali Lei, He Zhao, Jian Wang, and Zhuang Liu*


单位:

Institute of Functional Nano & Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Jiangsu 215123, China


摘要:

Multifunctional biodegradable inorganic theranostic nano-agents are of great interest to the field of nanomedicine. Upon lipid modification, VS2 nanosheets could be converted into ultra-small VS2 nanodots encapsulated inside polyethylene glycol (PEG) modified lipid micelles. Owing to paramagnetism, high near-infrared (NIR) absorbance, and chelator-free99mTc4+ labeling of VS2, such VS2@lipid-PEG nanoparticlescould be used for T1-weighted magnetic resonance (MR),photoacoustic (PA),and single photon emission computedtomography (SPECT) tri-modal imaging guided photothermalablation of tumors. Importantly, along with the gradualdegradation of VS2, our VS2@lipid-PEG nanoparticles exhibiteffective body excretion without appreciable toxicity. Theunique advantages of VS2 nanostructures with highly integrated functionalities and biodegradable behaviors mean they are promising for applications in cancer theranostics.


影响因子:

13.734


分区情况:

一区


链接:

http://onlinelibrary.wiley.com/doi/10.1002/anie.201707128/full



责任编辑:向丹婷



上一篇:揭建胜教授课题组和张秀娟教授课题组合作在Journal of Materials Chemistry C上发表文章
下一篇:刘庄教授课题组在Advanced Materials上发表论文

Copyright © 2012 苏州大学纳米科学技术学院 All Rights Reserved.
地址:苏州工业园区仁爱路199号910楼  邮编:215123
您是第位访问者