题目： | A practical and highly sensitive C3N4-TYR fluorescent probe for convenient detection of dopamine |
作者： | Hao Li,‡ Manman Yang,‡ Juan Liu, Yalin Zhang, Yanmei Yang, Hui Huang,* Yang Liu* and Zhenhui Kang* |
单位： | Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren’ai Road, Suzhou, 215123 Jiangsu, PR China. |
摘要： | The C3N4-tyrosinase (TYR) hybrid is a highly accurate, sensitive and simple fluorescent probe for the detection of dopamine (DOPA). Under optimized conditions, the relative fluorescence intensity of C3N4-TYR is proportional to the DOPA concentration in the range from 1 × 10−3 to 3 × 10−8 mol L−1 with a correlation coefficient of 0.995. In the present system, the detection limit achieved is as low as 3 × 10−8 mol L−1. Notably, these quantitative detection results for clinical samples are comparable to those of high performance liquid chromatography. Moreover, the enzyme-encapsulated C3N4 sensing arrays on both glass slide and test paper were evaluated, which revealed sensitive detection and excellent stability. The results reported here provide a new approach for the design of a multifunctional nanosensor for the detection of bio-molecules. |
影响因子： | 7.394 |
分区情况： | 1区 |
链接： | http://pubs.rsc.org/en/content/articlelanding/2015/nr/c5nr03316k |
