康振辉教授课题组在Journal of Materials Chemistry B上发表论文
题目: | Carbon dots from PEG for highly sensitive detection of levodopa† |
作者: | Hao Li, Juan Liu, Sijie Guo, Yalin Zhang, Hui Huang,* Yang Liu and Zhenhui Kang |
单位: | Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & So Materials (FUNSOM), Soochow University, 199 Ren'ai Road, Suzhou, 215123, Jiangsu, PR China. |
摘要: | High-intensity fluorescent carbon dots (CDs) coupled with tyrosinase (TYR) yielded hybrids, as a fluorescent probe, which were efficient, fast, stable and sensitive in the detection of levodopa (L-DOPA). The detection limit of L-DOPA was as low as 9.0 _ 10_8 mol L_1 with a wide linear range from 3.17 _ 10_4 mol L_1 to 3.11 _ 10_7 mol L_1. The efficient selective detection of L-DOPA can be attributed to the CDs that are excellent electron acceptors/donors and exhibit high adsorption capacity of H+. It is worth mentioning that TYR does not require modification and immobilization, and the test results could be read as soon as the probe–sample incubation was completed. Moreover, the test results are comparable to those of the present clinical fluorescence and high performance liquid chromatography (HPLC) methods. Our experimental results indicated that CDs possess great potential in the development of various enzymebased biosensors. |
影响因子: | 6.626 |
分区情况: | 1区 |
链接: | http://pubs.rsc.org/en/content/articlelanding/2015/tb/c4tb01983k |