我组宋宇翔在ACS Applied Energy Materials 上发表论文

题目：

Degradable Carbon Dots from Cigarette Smoking with BroadSpectrum Antimicrobial Activities against Drug-Resistant Bacteria

作者：

Yuxiang Song,† Fang Lu,‡ Hao Li,† Huibo Wang,† Mengling Zhang,† Yang Liu,*,† and Zhenhui Kang*,†

单位：

†Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, 199 Ren’ai Road, Suzhou 215123, Jiangsu P. R. China ‡ School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China

摘要：

Infection of pathogenic bacteria and the abuse of antibiotics are the main factors in worldwide health issues. A number of nanomaterials have been fabricated to directly battle drug-resistant bacteria. However, few studies have referred to the relation between common daily carbon nanoparticles (e.g., automobile exhaust and cigarette **oke) and antimicrobial activities. Herein, carbon dots (CDs) extracted from cigarette **oke are introduced, showing low in vivo and in vitro toxicity. These CDs show broadspectrum antimicrobial activities that originate from the destruction of the double helix structure of DNA. CDs can degrade to **aller particles and organic fragments with the existence of horseradish peroxidase (HRP) and H2O2 in 7 days, during which CDs can function as an effective antibiotic within the early days and then gradually degrade and lose the antimicrobial effects until finally being eliminated through metaboli**. Our findings relate common daily carbon nanoparticles from cigarette **oke with antimicrobial activities, suggesting that the CDs can function as an effective broadspectrum antibiotic, even against drug-resistant bacteria.

影响因子：

4.473

分区情况：

2区

链接：  

https://pubs.acs.org/doi/abs/10.1021/acsabm.8b00421