我组张梦玲在ACS Applied Materials & Interfaces上发表论文
Chiral Control of Carbon Dots via Surface Modification for Tuning the Enzymatic Activity of Glucose Oxidase | |
作者： | Mengling Zhang, Yurong Ma, Huibo Wang, Bo Wang, Yunjie Zhou, Yang Liu,* Mingwang Shao, Hui Huang,* Fang Lu,* and Zhenhui Kang* |
单位： | Suzhou University Soochow Univ, Inst Funct Nano & Soft Mat FUNSOM, Jiangsu Key Lab Carbon Based Funct Mat & Devices, Suzhou 215123, Peoples R China. Beijing University of Chinese Medicine Beijing Univ Chinese Med, Sch Life Sci, Beijing 100029, Peoples R China. Macau University of Science & Technology Macau Univ Sci & Technol, Macau Inst Mat Sci & Engn, Taipa 999078, Macao, Peoples R China. |
摘要： | Chiral carbon dots (CDs) integrated the advantages of achiral CDs and the unique chiral property, which expand the prospect of the biological applications of CDs. However, the structure control and the origin of chirality for chiral CDs remain unclear. Herein, chiral CDs were obtained by thermal polymerization of chiral amino acids and citric acid, and their handedness of chirality could be controlled by adjusting the reaction temperature, which leads to different kinds of surface modifications. With aliphatic amino acids as a chiral source, all of the CDs that reacted at different temperatures (90-200°C) have the same handedness of the chiral source. But with aromatic amino acids as a chiral source, CDs with maintained or inversed handedness compared with the chiral source could be obtained by adjusting the reaction temperature. Below a temperature of 120 degrees C, the chiral source was modified with CDs by esterification and transferred the handedness of chirality; at high temperatures (above 150 degrees C), which mainly connected by amidation accompanying with the formation of rigid structure generated by the it conjugation between the aromatic nucleus of chiral source and the carbon core of CDs, caused the inversing of the chiral signal. Further, we investigated the chiral effects of CDs on the glucose oxidase activity for a highly sensitive electrochemical biosensor. |
影响因子： | 8.758 |
分区情况： | 1区 |
链接： | https://pubs.acs.org/doi/10.1021/acsami.0c21949 |