题目：

Three-Dimensional BC/PEDOT Composite Nanofibers with High Performance for Electrode-Cell Interface

作者：

Chuntao Chen ^ab, Ting Zhang^c, Qi Zhang^c, Zhangqi Feng^*b, Chunlin Zhu^ab, Yalin Yu^b, Kangming Li^b, Mengyao Zhao^b, Jiazhi Yang^ab, Jian Liu^*c and Dongping Sun^*ab

单位：

^aInstitute of Chemicobiology and Functional Materials, Nanjing University of Science and Technology, 200 Xiao Ling Wei Street, Nanjing, Jiangsu Province, China.

^bSchool of Chemical Engineering, Nanjing University of Science and Technology, 200 Xiao Ling Wei Street, Nanjing, Jiangsu Province, China.

^cInstitute of Functional Nano and Soft Materials (FUNSOM), Soochow University, 199 Ren Ai Road, Suzhou Industrial Park, Suzhou, Jiangsu Province, China.

摘要：

There is an increasing need to synthesize biocompatible nanofibers with excellent mechanical and electrical performance for electrochemical and biomedical applications. Here we report a facile approach to prepare electroactive and flexible three-dimensional (3-D) nanostructured biomaterials with high performance based on bacterial cellulose (BC) nanofibers. Our approach can coat BC nanofibers with poly(3,4-ethylenedioxythiophene) (PEDOT) by in situ interfacial polymerization in a controllable manner. The PEDOT coating thickness is adjustable by the monomer concentration or reaction time during polymerization, producing nanofibers with a total diameter ranging from 30 to 200 nm. This fabrication process also provides a convenient method to tune different parameters such as the average pore size and electrical conductivity on the demands of actual applications. Our experiments have demonstrated that the 3-D BC/PEDOT nanofibers exhibit high specific surface area, excellent mechanical properties, electroactive stability, and low cell cytotoxicity. With electrical stimulation, calcium imaging of PC12 neural cells on BC/PEDOT nanofibers has revealed a significant increase in the percentage of cells with higher action potentials, suggesting an enhanced capacitance effect of charge injection. As an attractive solution to the challenge of designing better electrode-cell interfaces, 3-D BC/PEDOT nanofibers promise many important applications such as bio-sensing devices, smart drug delivery systems, and implantable electrodes for tissue engineering.

影响因子：

6.723

分区情况：

1区

链接：

http://pubs.acs.org/doi/pdf/10.1021/acsami.5b07273