Yao He is professor of Institute of Functional Nano&Soft Materials at Soochow University in China. He received his bachelor degree (2003) in chemistry from Fudan University (China), and continued the graduate study (Master and Doctor) in Fudan University (China) in 2003-2007. He was a visiting scholar for the joint program in Shanghai Institute of Applied Physics, Chinese Academy of Sciences (2005-2007). Afterwards, he worked in the Center of Super-Diamond and Advanced Films (COSDAF) in the City University of Hong Kong, HKSAR, China, as a research fellow. He became an associate professor (2009) and was promoted to full professor (2011) in Institute of Functional Nano & Soft Materials (FUNSOM) at Soochow University (China).
Email: yaohe@suda.edu.cn
Tel: 86-512-65880946, Fax: 86-512-65882846
Details
His research interests are in chemical biology and bioanalysis, nanotechnology, development of functional nanomaterials for bioapplications (e.g., bioimaging and biosensors), and biosafety assessment of nanomaterials. In particular, he developed functional silicon nanostructures with unique optical /thermal properties for bioimaging, biosensing, and cancer therapy applications, providing potentially promising tools for early cancer diagnosis and cancer treatment.
Starting from 2009 when Dr. He established his group, he has authored over 30 peer-reviewed papers with an impact factor (IF) lager than 7.0, 12 of which were published on top chemistry, materials and biomedicine journals (IF > 9.9) as the first author or corresponding authors, including 3 Angewandte Chemie and 1 JACS Cover. The awards Dr. He received include Science and Technology Award (the first prize) of Analysis and Testing Association of China (CAIA) in 2009, and Chinese Chemical Society Award for outstanding young scientist (10 awardees per year) in 2012. He served as a chief scientist of the “youth 973” project (National key scientific research projects) in 2013.
Reports on silicon nanostructures-based biosensing and bioimaging applications were published as Covers of J. Am. Chem. Soc., Angew. Chem. Int. Ed., and Appl. Phys. Lett.
10 recent representative papers published in the past two years (2010-)
1.Xiangxu Jiang, Ziyun Jiang, Tingting Xu, Shao Su, Yiling Zhong, Fei Peng, Yuanyuan Su, Yao He*. "SERS-Based Sensing in Vitro: Facile and Label-Free Detection of Apoptotic Cells at the Single-Cell Level" Anal. Chem.In press DOI: ac303337b (IF=5.856)
2.Xinpan Wei, Shao Su, Yuanyuan Guo, Xiangxu Jiang, Yiling Zhong, Yuanyuan Su, Chunhai Fan, Shuit-Tong Lee, Yao He*. "A Molecular Beacon-Based Signal-Off Raman-Surface Enhanced Scattering Strategy for Highly Sensitive, Reproducible and Multiplexed DNA Detection" SmallIn press DOI: 10.1021/ac03337b (IF=8.349)
3.Yimei Lu, Yuanyuan Su*, Yanfeng Zhou, Jie Wang, Pei Peng, Yiling Zhong, Qing Huang, Chunhai Fan, Yao He*. "In vivo behavior of near infrared-emitting quantum dots"BiomaterialsIn press DOI: jbmt23574 (IF=7.404)
4.Fei Peng, Yuanyuan Su, Xinpan Wei, Yimei Lu, Yanfeng Zhou, Yiling Zhong, Shuit-Tong Lee*, Yao He*. "Silicon Nanowires-Based Nanocarriers with Ultrahigh Drug-Loading Capacity for in vitro and in vivo Cancer Therapy" Angew. Chem. Int. Ed. 2013, 52,1457-1461 (IF=13.455)
5.Yiling Zhong, Fei Peng, Xinpan Wei, Yanfeng Zhou, Jie Wang, Xiangxu Jiang, Yuanyuan Su, Shao Su, Shuit-Tong Lee*, Yao He*. "Microwave-assisted synthesis of biofunctional and fluorescent silicon nanoparticles using protein as hydrophilic ligands" Angew. Chem. Int. Ed. 2012, 51, 8485-8489 (IF=13.455)
6.Yuanyuan Su, Xinpan Wei, Fei Peng, Yiling Zhong, Yimei Lu, Shao Su, Tingting Xu, Shuit-Tong Lee*, Yao He*. "Gold nanoparticles-decorated silicon nanowires as highly efficient near-infrared hyperthermia agents for cancer cells destruction" Nano Lett. 2012, 12, 1845-1850 (IF=13.198)
7.Shao Su, Xinpan Wei, Yiling Zhong, Yuanyuan Guo, Yuanyuan Su, Qing Huang, Shuit-Tong Lee*, Chunhai Fan*, Yao He*. "Silicon nanowire-based molecular beacons for high-sensitivity and sequence-specific DNA multi-analysis" ACS Nano 2012, 6, 2582-2590 (IF=10.744)
8.Yao He*, Yiling Zhong, Fei Peng, Xinpan Wei, Yuanyuan Su, Yimei Lu, Shao Su, Wei Gu, Liangsheng Liao, Shuit-Tong Lee*. "One-Pot Microwave Synthesis of Water-Dispersible, Ultraphoto and pH Stable, and Highly Fluorescent Silicon Quantum Dots"J. Am. Chem. Soc.2011, 133, 14192-14195. (IF=9.907)
9.Yao He*, Yiling Zhong, Yuanyuan Su, Yimei Lu, Ziyun Jiang, Fei Peng, Tingting Xu, Shao Su, Qing Huang, Chunhai Fan*, Shuit-Tong Lee*. "Water-Dispersed Near-Infrared-Emitting Quantum Dots of Ultrasmall Sizes for in Vitro and in Vivo Imaging" Angew. Chem. Int. Ed.2011, 123, 5813-5816.(IF=13.198)
10.Yao He*, Yiling Zhong, Fei Peng, Xinpan Wei, Yuanyuan Su, Shao Su, Wei Gu, Liangsheng Liao, Shuit-Tong Lee*. "Highly luminescent water-dispersible silicon nanowires for long-term immunofluorescent cellular imaging" Angew. Chem. Int. Ed.2011, 50, 3080-3083. (IF=13.455)
