题目：

A Self-Assembled Albumin-Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging

作者：

¹Qian Chen, ²Xiaodong Liu, ¹Jiawen Chen, ³Jianfeng Zeng,*         ²Zhenping Cheng, and ¹Zhuang Liu*

单位：

¹Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University Suzhou, Jiangsu215123, China.

²Department of Polymer Science and Engineering, Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application College of Chemistry Chemical Engineering and Materials Science  Soochow University Suzhou, Jiangsu 215123, China.

³School of Radiation Medicine and Protection Medical College of Soochow University, Suzhou, Jiangsu 215123, China.

摘要：

A photoacoustic nanoprobe is self-assembled from human serum albumin and two types of dye molecules, one is inert to pH and the other is pH sensitive. This probe and the quantitative ratiometric photoacoustic pH imaging method are shown to have high safety, be easy-to-operate, and have depth-independent accuracy for real-time in vivo pH imaging of entire tumors. These features make them promising for future cancer prognosis and therapeutic planning.

影响因子：

17.493

分区情况：

一区

链接：

http://onlinelibrary.wiley.com/doi/10.1002/adma.201503194/full