题目：

A practical and highly sensitive C₃N₄-TYR fluorescent Probe for Convenient Detection of Dopamine

作者：

Hao Li,^‡ Manman Yang,^‡ Juan Liu, Yalin Zhang, Yanmei Yang, Hui Huang,* Yang Liu* and Zhenhui Kang*

单位：

Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University

摘要：

The C₃N₄-tyrosinase (TYR) hybrid is a highly accurate, sensitive and simple fluorescent probe for the detection of dopamine (DOPA). Under optimized conditions, the relative fluorescence intensity of C₃N₄-TYR is proportional to the DOPA concentration in the range from 1 × 10⁻³ to 3 × 10⁻⁸ mol L⁻¹ with a correlation coefficient of 0.995. In the present system, the detection limit achieved is as low as 3 × 10−8 mol L⁻¹. Notably, these quantitative detection results for clinical samples are comparable to those of high performance liquid chromatography. Moreover, the enzyme-encapsulated C3N4 sensing arrays on both glass slide and test paper were evaluated, which revealed sensitive detection and excellent stability. The results reported here provide a new approach for the design of a multifunctional nanosensor for the detection of bio-molecules.

影响因子：

7.394

分区情况：

1区

链接：

http://pubs.rsc.org/en/content/articlelanding/2015/nr/c5nr03316k