报告人： Prof. William A. Goddard, III (Director of Caltech-Soochow Multiscale nanoMaterials Genome Center (MnG); FUNSOM, Soochow University, Suzhou China; Charles and Mary Ferkel Professor of Chemistry, Materials Science, and Applied Physics; Director, Materials and Process Simulation Center (MSC), California Institute of Technology (139-74), Pasadena, CA 91125, UAS)

报告题目：Molecular Dynamics Simulations of nanoBiomacromolecular systems

报告时间：2：00 pm, Oct. 17(Thursday)

报告地点：909-B

Abstract: 

Advances in the methods for Molecular Dynamics (MD) Simulations of Biomacromolecular systems including

omplete Sampling methods for in silico predictions of 3D structures for G-Protein Coupled Receptors (GPCRs) (GEnSeMBLE) and of binding sites (DarwinDock)

The roles of agonist, G-Protein, and GPCR in G-Protein and β-arrestin signaling

 a) Class A: μ and κ Opioid and beta2 adrenergic GPCRs

b) Class A Tas2R4 and Tas2R14 taste GPCRs

c) class C Tas1R2:1R3 heterodimer and Tas1R3 homodimer sweet GPCRs

A new generation of programmable drugs that switch on only for diseased cells and then kill the cell: cell selective RNAi therapy with conditionally activated siRNAs.

联系人：程涛 教授

责任编辑：杨娟