周炀 副教授

教育经历

2017/09-2022/06：苏州大学，功能纳米与软物质研究院，化学，理学博士

2013/09-2017/06：苏州大学，纳米科学技术学院，纳米材料与技术，工学学士

工作经历

2025/9-至今：苏州大学，功能纳米与软物质研究院，副教授

2023/01-2025/06：苏州大学，功能纳米与软物质研究院，博士后

2022/07-2022/12：西湖大学，程建军教授课题组，访问学者

所在课题组

殷黎晨教授课题组

联系方式

江苏省苏州市工业园区仁爱路199号，912-0305

邮箱：yangzhou@suda.edu.cn

个人荣誉

1. 入选苏州大学“优秀青年学者”（2025）

2. 入选Wiley China Excellent Author Program（2024）

3. 入选江苏省卓越博士后计划（2023）

主持项目

1. 国家自然科学基金委员会，青年基金项目（主持）

2. 中国博士后科学基金会，第73批面上资助（主持）

研究领域

1. 基于仿生纳米材料的炎症介质清除系统

2. 基于构象可转变聚多肽的免疫调控纳米系统

3. 穿透生理屏障的基因/药物递送系统

代表性研究成果

截止目前，共参与发表SCI论文27篇，其中以第一作者或通讯作者身份在Sci. Adv.、J. Am. Chem. Soc.、Adv. Mater.、ACS Nano、Adv. Funct. Mater.、Nano Today、J. Control. Release等高水平期刊发表论文19篇。

代表性论文

1. Yang Zhou^#, Huan Ye^#, Yi Yu, Chenglong Ge, Mengyuan Yin, Zhongmin Liu, Jingrui Shen, Renxiang Zhou, Youyong Li*, Kam W. Leong*, Lichen Yin*. Helix-guarded molecular clips for cell-free DNA scavenging and treatment of systemic lupus erythematosus. J. Am. Chem. Soc. 2025, 147, 6612-6622.

2. Yang Zhou, Zhiyong Liu, Mengyuan Yin, Chenglong Ge, Zhongmin Liu, Renxiang Zhou, Duanmin Hu*, Lichen Yin*. Multi-target nanoscavengers for interrupting the feed-forward inflammatory cycle in autoimmune diseases. Adv. Funct. Mater. 2025, in press.

3. Wenhan Zhao^#, Yang Zhou^#, Lichen Yin*. Cell-free DNA-scavenging nano/microsystems for immunotherapy. J. Control. Release 2025, 381, 113609.

4. Jingrui Shen, Yang Zhou*, Lichen Yin*. Nano/genetically engineered cells for immunotherapy. BMEMat 2025, 3, e12112.

5. Fuwei Qi^#, Yinsheng Liao^#, Chenglong Ge, Yiyao Yang, Junliang Zhu, Jiang Zhu*, Yang Zhou*, Hong Xie*, Lichen Yin*. Intranasally delivered echinacoside micelles modulate mitochondrial fusion against postoperative cognitive dysfunction. Adv. Funct. Mater. 2025, DOI: 10.1002/adfm.202505499.

6. Zhongmin Liu, Jing Yan, Yang Zhou*, Mengyuan Yin, Renxiang Zhou, Jingrui Shen, Duanmin Hu*, Lichen Yin*. Biomimetic immunoregulators for the multi-target inflammation interruption in autoimmune disease. ACS Nano 2025, 19, 27294-27309.

7. Mengyuan Yin^#, Chenglong Ge^#, Yang Zhou^#, Renxiang Zhou, Yiyao Yang, Yu Qian, Jianyin He, Jingrui Shen, Lichen Yin*. Inflammation-activatable nanoscavengers for sustainable cell-free DNA capture and cleavage. Adv. Mater. 2025, DOI: 10.1002/adma.202504557.

8. Renxiang Zhou^#, Yang Zhou^#, Mengyuan Yin, Chenglong Ge, Yiyao Yang, Jingrui Shen, Lichen Yin*. Inflammation-responsive polyion complex vesicles for autoimmune disease therapy via cell-free DNA scavenging and inflammatory microenvironment modulation. ACS Nano 2024, 18, 30017-30030.

9. Qinghua Wu^#, Yang Zhou^#, Jing Yan, Xudong Li, Fenghua Meng*, Bin Wang*, Lichen Yin*. Biomimetic nanocomplexes orchestrate post-stroke cerebral microenvironment via microglia-targeted siRNA delivery. Nano Today 2024, 58, 102444.

10. Mengyuan Yin, Zhongmin Liu, Yang Zhou*, Wei Li, Jing Yan, Desheng Cao, Lichen Yin*. Two-pronged anti-cancer nanovaccines enpowered by exogenous/ endogenous tumor-associated antigens. J. Control. Release 2024, 373, 358-369.

11. Wenxin Zhang^#, Jingrui Shen^#, Jialong Liang, Chenglong Ge, Yang Zhou*, Lichen Yin*, Yong Ji*. Pulmonary RNA interference against acute lung injury mediated by mucus- and cell-penetrating nanocomplexes. Acta Biomater. 2024, 177, 332-346.

12. Bingchen Shan^#, Yang Zhou^#, Mengyuan Yin, Yekun Deng, Chenglong Ge, Zhongmin Liu, Renxiang Zhou, Qirong Dong*, Xiaozhong Zhou*, Lichen Yin*. Macrophage membrane-reversibly cloaked nanotherapeutics for the anti-inflammatory and antioxidant treatment of rheumatoid arthritis. Small Methods 2023, 7, 2300667.

13. Jianhui Lu^#, Jiaheng Zhang^#, Wen Yan, Chenglong Ge, Yang Zhou*, Rongying Zhu, Shanzhou Duan, Lichen Yin*, Yongbing Chen*. MicroRNA-208a silencing against myocardial ischemia/reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes. Nano Res. 2023, 16, 11176-11185.

14. Yang Zhou^#, Qiujun Liang^#, Xuejie Wu, Shanzhou Duan, Chenglong Ge, Huan Ye, Jianhui Lu, Rongying Zhu, Yongbing Chen, Fenghua Meng, Lichen Yin*. siRNA delivery against myocardial ischemia reperfusion injury mediated by reversibly camouflaged biomimetic nanocomplexes. Adv. Mater. 2023, 35, 2210691.

15. Yang Zhou^#, Yekun Deng^#, Zhongmin Liu, Mengyuan Yin, Mengying Hou, Ziyin Zhao, Xiaozhong Zhou, Lichen Yin*. Cytokine-scavenging nanodecoys reconstruct osteoclast/osteoblast balance toward the treatment of postmenopausal osteoporosis. Sci. Adv. 2021, 7, eabl6432.

16. Yekun Deng^#, Yang Zhou^#, Qiujun Liang, Chenglong Ge, Jiandong Yang, Bingchen Shan, Yong Liu, Xiaozhong Zhou*, Lichen Yin*. Inflammation-instructed hierarchical delivery of IL-4/miR-21 orchestrates osteoimmune microenvironment toward the treatment of rheumatoid arthritis. Adv. Funct. Mater. 2021, 31, 2101033.

17. Huan Ye^#, Yang Zhou^#, Xun Liu, Yongbing Chen*, Shanzhou Duan, Rongying Zhu, Yong Liu*, Lichen Yin*. Recent advances on reactive oxygen species-responsive delivery and diagnosis system. Biomacromolecules 2019, 20, 2441-2463.

18. Yang Zhou^#, Huan Ye^#, Yongbing Chen, Rongying Zhu, Lichen Yin*. Photoresponsive drug/gene delivery systems. Biomacromolecules 2018, 19, 1840-1857.

19. Wenxin Zhang^#, Yang Zhou^#, Xudong Li, Xin Xu, Yongbing Chen*, Rongying Zhu, Lichen Yin*. Macrophage-targeting and reactive oxygen species (ROS)-responsive nanopolyplexes mediate anti-inflammatory siRNA delivery against acute liver failure (ALF). Biomater. Sci. 2018, 6, 1986-1993.

责任编辑：杨娟