
许方
讲师,硕士生导师,苏州大学优秀青年学者
教育工作经历
2020年6月获南京大学博士学位,2020年8月至2023年7月在苏州大学功能纳米与软物质研究院从事博士后研究,2023年8月入职苏州大学功能纳米与软物质研究院。
所在课题组:汪超教授课题组
研究领域与成果
近年来围绕生物材料的工程化改造及其在免疫调控和相关疾病治疗中的应用,开发了多种工程化生物材料(如工程化细胞外囊泡、工程化细菌等),通过调控免疫微环境,用于自身性免疫疾病、肿瘤及炎性相关疾病的治疗。以第一作者/通讯作者(含共同)在PNAS、Cell Reports、Advanced Materials、ASC Nano、Biomaterials等国际知名学术期刊发表多篇论文,并授权3项中国发明专利,主持中国博士后面上项目、国家自然科学基金青年基金项目、苏州市科技发展计划项目、苏州市应用基础研究(医疗卫生)科技创新青年项目等。
代表性论文(入职后):
[1] Xiaoyu Yu, Shuqi Chen, Rong Sun, Chenlu Yao, Bingbing Wu, Heng Wang, Chenhui Weng, Dongdong Sun*, Chao Wang*, Fang Xu*. Engineered Dendritic Cell-Derived Vesicles for T-Cell-Targeted Magnesium Delivery and Metabolic Reprogramming. ACS Nano, 2025, 19, 41184-41199.
[2] Chenmeng Zhou, Yue Zhang, Bo Tian, Yue Yu, Dongxiao Li, Bingbing Wu, Wenju Chang, Tongguo Shi, Fang Xu*, Jinyu Bai* and Chao Wang*. Bacteria-responsive cytoderm drug delivery systems. Biomaterials Science. 2025, 13, 2744–2754.
[3] Fang Xu, Chao Wang* “Immunomodulation: precision targeting for restoring immune homeostasis and therapeutic applications”Essays in Biochemistry. 2025, 69 (02), 19–21.
[4] Heng Wang, Fang Xu*, Chenlu Yao, Huaxing Dai, Jialu Xu, Bingbing Wu, Bo Tian, Xiaolin Shi, Chao Wang*. Engineering bacteria for cancer immunotherapy by inhibiting IDO activity and reprogramming CD8+ T cell response. Proceedings of the National Academy of Sciences, 2024, 121(52), e2412070121.
[5] Bingbing Wu, Chenlu Yao, Heng Wang, Huaxing Dai, Bo Tian, Dongxiao Li, Jialu Xu, Haibo Cheng, Fang Xu*, Dongdong Sun*, Chao Wang*. Ellagic acid-protein nano-complex inhibits tumor growth by reducing the intratumor bacteria and inhibiting histamine production. Biomaterials, 2024, 317, 123078.
[6]Yi Wu, Heng Wang, Anning Song, Xiaoyu Wang, Qingle Ma, Chenlu Yao, Jialu Xu, Huaxing Dai, Chao Wang*, Ting Lu*, Fang Xu*. PD-L1-Expressing Extracellular Vesicles for the Treatment of Pneumonia. ACS Biomater. Sci. Eng., 2023, 9, 6464–6471.
开授课程:《普通生物学》、《综合生物学实验II》
联系方式:fangx@suda.edu.cn
责任编辑:杨娟