题目：

A Self-Assembled Albumin-Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging

作者：

Qian Chen,1 Xiaodong Liu,² Jiawen Chen,¹ Jianfeng Zeng,*^,3 Zhenping Cheng,² and Zhuang Liu^1,*

单位：

¹Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University Suzhou, Jiangsu215123, China

²Department of Polymer Science and Engineering, Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou, Jiangsu 215123, China

³School of Radiation Medicine and Protection Medical College of Soochow University, Suzhou, Jiangsu 215123, China

摘要：

A photoacoustic nanoprobe is self-assembled from human serum albumin and two types of dye molecules, one is inert to pH and the other is pH sensitive. This probe and the quantitative ratiometric photoacoustic pH imaging method are shown to have high safety, be easy-to-operate, and have depth-independent accuracy for real-time in vivo pH imaging of entire tumors. These features make them promising for future cancer prognosis and therapeutic planning.

影响因子：

17.493

分区情况：

1区

链接：

http://onlinelibrary.wiley.com/doi/10.1002/adma.201503194/full

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