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程亮
教授、博士生导师




程亮

苏州大学功能纳米与软物质研究院特聘教授,博士生导师。

2019年入选国家级人才工程

 

2012年苏州大学获得博士学位,之后留校工作被聘为讲师。20147月晋升为副教授;20178月晋升为研究员;201911月晋升为特聘教授。2015~2016年期间在美国威斯康辛大学-麦迪逊分校访学交流。

  

主要成果和技术贡献:

近年来从材料科学领域出发,结合多学科交叉研究的优势,在纳米生物医学等领域从事科学研究。发展了多种无机纳米材料及其复合功能纳米材料,利用其独特的光学、磁学和X-射线吸收等性质,探索了针对肿瘤影像导航下的肿瘤光学治疗和联合治疗,并证明了这些功能材料在实现精准治疗和提高肿瘤治疗的特异性等方面具有独特的优势。

2009年起在国际学术期刊共发表学术论文174篇,论文SCI总他引17661次,SCI “H-index”66(数据来自Web of science)。其中第一/通讯作者67篇,发表于Chem. Rev.1篇)、Chem. Soc. Rev.1篇)、Nat. Commun.1篇)、J. Am. Chem. Soc.1篇)、Angew. Chem. Int. Ed.4篇)、Adv. Mater.3篇)、Natl. Sci. Rev.1篇)、Nano Today2篇)、Mater. Hor.2篇)、Nano Lett.篇)、ACS Nano6篇)、Adv. Funct. Mater.5篇)、Small4篇)、Biomaterials4篇)等材料、化学领域权威期刊。29SCI论文被选为“ESI高被引论文,最高单篇他引1295次。2017-2020连续四年入选美国科睿唯安公布的全球高被引科学家名单Highly Cited Researchers)(材料);2017-2019连续三年入选爱思唯尔发布的中国高被引学者(材料)。研究成果先后受到C&ENMaterials ViewsMaterials Views ChinaX-MOL等众多媒体和网站的亮点报道。获得国家自然科学区域发展联合基金、青年基金及面上项目、江苏省自然科学优秀青年基金等项目资助,并入选苏州大学仲英学者东吴学者、江苏省333人才工程。担任国际著名期刊杂志《Journal of Nanobiotechnology》副主编(IF=6.518)。

 

招生方向:

本研究方向热忱欢迎有志从事科研工作的本科生、研究生到课题组学习工作。招生方向为材料科学与工程04方向,生物纳米材料与生物医学材料)。欢迎具有化学、材料、或生物医学背景的同学报考。有疑问请随时邮件联系lcheng2@suda.edu.cn


博士后招聘:

课题组近年来获多方支持发展,组内科研氛围浓厚,积极向上,师生关系融洽。现面向海内外诚聘优秀博士加盟。


招聘方向

(1)  功能无机纳米材料合成与应用

(2)  无机纳米酶的构建与应用

(3)  肿瘤微环境调控及纳米生物学效应

(4)  可穿戴器件构建及其应用

 

发表论文
http://www.researcherid.com/rid/K-9840-2015

https://scholar.google.com/citations?user=qXNS1XUAAAAJ&hl=zh-CN

  

近五年代表性论文(2016-2020)

1.  Zhou, Z.; Wang, X.; Zhang, H.; Huang, H.; Sun, L.; Ma, L.; Du, Y.; Pei, C.; Zhang, Q.; Li, H.; Ma, L.; Gu, L.; Liu, Z.; Cheng, L*.; Tan, C.*, Activating Layered Metal Oxide Nanomaterials via Structural Engineering as Biodegradable Nanoagents for Photothermal Cancer Therapy. Small 2021, ASAP.

2.  Zhang, R.; Cheng, L.*; Dong, Z.; Hou, L.; Zhang, S.; Meng, Z.; Betzer, O.; Wang, Y.; Popovtzer, R.; Liu, Z.*; Ultra-small natural product based coordination polymer nanodots for acute kidney injury relief, Materials Horizons2021, ASAP.

3.  Gong, F.; Cheng, L.*; Yang, N.; Gong, Y.; Ni, Y.; Bai, S.; Wang, X.; Chen, M.; Chen, Q.; Liu, Z.*, Preparation of TiH1.924 nanodots by liquid-phase exfoliation for enhanced sonodynamic cancer therapy. Nature Communications 2020,11 (1), 3712.

4.  Wang, X.; Zhong, X.; Bai, L.; Xu, J.; Gong, F.; Dong, Z.; Yang, Z.; Zeng, Z.; Liu, Z.; Cheng, L.*, Ultrafine Titanium Monoxide (TiO1+x) Nanorods for Enhanced Sonodynamic Therapy. Journal of the American Chemical Society 2020,142 (14), 6527-6537.

5.  Son, S.; Kim, J. H.; Wang, X.; Zhang, C.; Yoon, S. A.; Shin, J.; Sharma, A.*; Lee, M. H.*; Cheng, L.*; Wu, J.*; Kim, J. S.*, Multifunctional sonosensitizers in sonodynamic cancer therapy. Chemical Society Reviews 2020,49 (11), 3244-3261.

6.  Cheng, L.*; Wang, X.; Gong, F.; Liu, T.; Liu, Z.*, 2D Nanomaterials for Cancer Theranostic Applications. Advanced Materials 2020,32 (13), 1902333.

7.  Gong, F.; Yang, N.; Wang, X.; Zhao, Q.; Chen, Q.; Liu, Z.; Cheng, L.*, Tumor microenvironment-responsive intelligent nanoplatforms for cancer theranostics. Nano Today 2020,32, 100851.

8.  Gong, F.; Chen, M.; Yang, N.; Dong, Z.; Tian, L.; Hao, Y.; Zhuo, M.; Liu, Z.; Chen, Q.*; Cheng, L.*, Bimetallic Oxide FeWOx Nanosheets as Multifunctional Cascade Bioreactors for Tumor Microenvironment-Modulation and Enhanced Multimodal Cancer Therapy. Advanced Functional Materials 2020,30 (49), 2002753.

9.  Wang, X.; Zhong, X.; Liu, Z.; Cheng, L.*, Recent progress of chemodynamic therapy-induced combination cancer therapy. Nano Today 2020,35, 100946.

10.  Wang, X.; Zhong, X.; Gong, F.; Chao, Y.; Cheng, L.*, Newly developed strategies for improving sonodynamic therapy. Materials Horizons 2020,7 (8), 2028-2046.

11.  Wang, X.; Wang, X.; Zhong, X.; Li, G.; Yang, Z.; Gong, Y.; Liu, Z.*; Cheng, L.*, V-TiO2 nanospindles with regulating tumor microenvironment performance for enhanced sonodynamic cancer therapy. Applied Physics Reviews 2020,7 (4), DOI: 10.1063/5.0027606.

12.  Wang, X.; Fan, L.; Cheng, L.*; Sun, Y.; Wang, X.; Zhong, X.; Shi, Q.; Gong, F.; Yang, Y.; Ma, Y.; Miao, Z.; Zha, Z.*, Biodegradable Nickel Disulfide Nanozymes with GSH-Depleting Function for High-Efficiency Photothermal-Catalytic Antibacterial Therapy. Iscience 2020,23 (7), 101281.

13.  Wang, X.; Cheng, L.*, Multifunctional Prussian blue-based nanomaterials: Preparation, modification, and theranostic applications. Coordination Chemistry Reviews 2020,419.

14.  Zhong, X.; Wang, X.; Cheng, L.*; Tang, Y. a.; Zhan, G.; Gong, F.; Zhang, R.; Hu, J.*; Liu, Z.; Yang, X.*, GSH-Depleted PtCu3 Nanocages for Chemodynamic- Enhanced Sonodynamic Cancer Therapy. Advanced Functional Materials 2020,30 (4). 1907954.

15.  Yang, N.; Li, W.; Gong, F.; Cheng, L.*; Dong, Z.; Bai, S.; Xiao, Z.; Ni, C.*; Liu, Z.*, Injectable Nonmagnetic Liquid Metal for Eddy-Thermal Ablation of Tumors under Alternating Magnetic Field. Small Methods 2020,4 (9), 2000147.

16.  Gong, F.; Yang, N.; Wang, Y.; Zhuo, M.; Zhao, Q.*; Wang, S.; Li, Y.; Liu, Z.; Chen, Q.; ChengL.*, Oxygen-Deficient Bimetallic Oxide FeWOX Nanosheets as Peroxidase-Like Nanozyme for Sensing Cancer via Photoacoustic Imaging. Small 2020,16 (46), 2003496.

17.  Siwawannapong, K.; Zhang, R.; Lei, H.; Jin, Q.; Tang, W.; Dong, Z.; Lai, R.-Y.; Liu, Z.; Kamkaew, A.*; Cheng, L.*, Ultra-small Pyropheophorbide-a Nanodots for Near-infrared Fluorescence/Photoacoustic Imaging-guided Photodynamic Therapy. Theranostics 2020,10 (1), 62-73.

18.  Lei, H.; Wang, X.; Bai, S.; Gong, F.; Yang, N.; Gong, Y.; Hou, L.; Cao, M.*; Liu, Z.; Cheng, L.*, Biodegradable Fe-Doped Vanadium Disulfide Theranostic Nanosheets for Enhanced Sonodynamic/Chemodynamic Therapy. ACS Applied Materials & Interfaces 2020,12 (47), 52370-52382.

19.  Bai, S.; Yang, N.; Wang, X.; Gong, F.; Dong, Z.; Gong, Y.; Liu, Z.*; Cheng, L.*, Ultrasmall Iron-Doped Titanium Oxide Nanodots for Enhanced Sonodynamic and Chemodynamic Cancer Therapy. ACS Nano 2020,14 (11), 15119-15130.

20.  Zhong, X.; Wang, X.; Zhan, G.; Tang, Y. a.; Yao, Y.; Dong, Z.; Hou, L.; Zhao, H.; Zeng, S.; Hu, J.*; Cheng, L*.; Yang, X.*, NaCeF4:Gd,Tb Scintillator as an X-ray Responsive Photosensitizer for Multimodal Imaging-Guided Synchronous Radio/Radiodynamic Therapy. Nano Letters 2019,19 (11), 8234-8244.

21.  Zhang, R.; Fan, X.; Meng, Z.; Lin, H.; Jin, Q.; Gong, F.; Dong, Z.; Li, Y.; Chen, Q.; Liu, Z.; Cheng, L.*, Renal Clearable Ru-based Coordination Polymer Nanodots for Photoacoustic Imaging Guided Cancer Therapy. Theranostics 2019,9 (26), 8266-8276.

22.  Xu, Y.; Wang, X.; Cheng, L.*; Liu, Z.; Zhang, Q.*, High-yield synthesis of gold bipyramids for in vivo CT imaging and photothermal cancer therapy with enhanced thermal stability. Chemical Engineering Journal 2019,378.

23.  Xiao, J.; Cheng, L.*; Fang, T.; Zhang, Y.; Zhou, J.; Cheng, R.; Tang, W.; Zhong, X.; Lu, Y.; Deng, L.; Cheng, Y.*; Zhu, Y.; Liu, Z.; Cui, W.,* Nanoparticle-Embedded Electrospun Fiber-Covered Stent to Assist Intraluminal Photodynamic Treatment of Oesophageal Cancer. Small 2019,15 (49).

24.  Wang, X.; Zhong, X.; Lei, H.; Geng, Y.; Zhao, Q.*; Gong, F.; Yang, Z.; Dong, Z.; Liu, Z.; Cheng, L.*, Hollow Cu2Se Nanozymes for Tumor Photothermal-Catalytic Therapy. Chemistry of Materials 2019,31 (16), 6174-6186.

25.  Wang, X.; Cheng, L.*, Multifunctional two-dimensional nanocomposites for photothermal-based combined cancer therapy. Nanoscale 2019,11 (34), 15685-15708.

26.  Tang, W.; Dong, Z.; Zhang, R.; Yi, X.; Yang, K.; Jin, M.; Yuan, C.;* Xiao, Z.*; Liu, Z.; Cheng, L.*, Multifunctional Two-Dimensional Core-Shell MXene@Gold Nanocomposites for Enhanced Photo-Radio Combined Therapy in the Second Biological Window. ACS Nano 2019,13 (1), 284-294.

27.  Liu, T.; Shen, S.; Huang, Y.; Zhang, X.; Lai, Z.; Ha Tran, T.; Liu, Z.; Cheng, L.*, Controllable growth of Au nanostructures onto MoS2 nanosheets for dual-modal imaging and photothermal-radiation combined therapy. Nanoscale 2019,11 (47), 22788-22795.

28.  Gong, F.; Cheng, L.*; Yang, N.; Betzer, O.; Feng, L.; Zhou, Q.; Li, Y.; Chen, R.; Popovtzer, R.; Liu, Z.*, Ultrasmall Oxygen-Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy. Advanced Materials 2019,31 (23)1900730.

29.  Wu, C.; Zhang, R.; Du, W.; Cheng, L.*; Liang, G.*, Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors. Nano Letters 2018,18 (12), 7749-7754.

30.  Jin, Q.; Liu, J.; Zhu, W.; Dong, Z.; Liu, Z.; Cheng, L.*, Albumin-Assisted Synthesis of Ultrasmall FeS2 Nanodots for Imaging-Guided Photothermal Enhanced Photodynamic Therapy. Acs Applied Materials & Interfaces 2018,10 (1), 332-340.

31.   Gong, F.; Cheng, L.*; Yang, N.; Jin, Q.; Tian, L.; Wang, M.; Li, Y.; Liu, Z.*, Bimetallic Oxide MnMoOx Nanorods for in Vivo Photoacoustic Imaging of GSH and Tumor-Specific Photothermal Therapy. Nano Letters 2018,18 (9), 6037-6044.

32.  Shen, S.; Jiang, D.; Cheng, L.*; Chao, Y.; Nie, K.; Dong, Z.; Kutyreff, C. J.; Engle, J. W.; Huang, P.; Cai, W.*; Liu, Z.*, Renal-Clearable Ultrasmall Coordination Polymer Nanodots for Chelator-Free Cu-64-Labeling and Imaging-Guided Enhanced Radiotherapy of Cancer. ACS Nano 2017,11 (9), 9103-9111.

33.  Shen, S.; Chao, Y.; Dong, Z.; Wang, G.; Yi, X.; Song, G.; Yang, K.; Liu, Z.; Cheng, L.*, Bottom-Up Preparation of Uniform Ultrathin Rhenium Disulfide Nanosheets for Image-Guided Photothermal Radiotherapy. Advanced Functional Materials 2017,27 (28), 1700250.

34.  Jin, Q.; Zhu, W.; Jiang, D.; Zhang, R.; Kutyreff, C. J.; Engle, J. W.; Huang, P.; Cai, W.*; Liu, Z.; Cheng, L.*, Ultra-small iron-gallic acid coordination polymer nanoparticles for chelator-free labeling of Cu-64 and multimodal imaging-guided photothermal therapy. Nanoscale 2017,9 (34), 12609-12617.

35.  Hao, J.; Song, G.; Liu, T.; Yi, X.; Yang, K.; Cheng, L.*; Liu, Z.*, In Vivo Long-Term Biodistribution, Excretion, and Toxicology of PEGylated Transition-Metal Dichalcogenides MS2 (M = Mo, W, Ti) Nanosheets. Advanced Science 2017,4 (1), 1600160.

36.  Cheng, L.*; Shen, S.; Jiang, D.; Jin, Q.; Ellison, P. A.; Ehlerding, E. B.; Goel, S.; Song, G.; Huang, P.; Barnhart, T. E.; Liu, Z.*; Cai, W.*, Chelator-Free Labeling of Metal Oxide Nanostructures with Zirconium-89 for Positron Emission Tomography Imaging. ACS Nano 2017,11 (12), 12193-12201.

37.  Cheng, L.*; Jiang, D.; Kamkaew, A.; Valdovinos, H. F.; Im, H.-J.; Feng, L.; England, C. G.; Goel, S.; Barnhart, T. E.; Liu, Z.; Cai, W.*, Renal-Clearable PEGylated Porphyrin Nanoparticles for Image-Guided Photodynamic Cancer Therapy. Advanced Functional Materials 2017,27 (34), 1702928.

38.  Chen, Y.; Cheng, L.*; Dong, Z.; Chao, Y.; Lei, H.; Zhao, H.; Wang, J.; Liu, Z.*, Degradable Vanadium Disulfide Nanostructures with Unique Optical and Magnetic Functions for Cancer Theranostics. Angewandte Chemie International Edition 2017,56 (42), 12991-12996.

39.  Xuan, J.; Wang, Z.; Chen, Y.; Liang, D.; Cheng, L.*; Yang, X.; Liu, Z.; Ma, R.; Sasaki, T.; Geng, F.*, Organic-Base-Driven Intercalation and Delamination for the Production of Functionalized Titanium Carbide Nanosheets with Superior Photothermal Therapeutic Performance. Angewandte Chemie International Edition 2016,55 (47), 14569-14574.

40.  Liu, T.; Chao, Y.; Gao, M.; Liang, C.; Chen, Q.; Song, G.; Cheng, L.*; Liu, Z.*, Ultra-small MoS2 nanodots with rapid body clearance for photothermal cancer therapy. Nano Research 2016,9 (10), 3003-3017.

41.  Cheng, L.; Shi, S.; Shen, S.; Barnhart, T.; Cai, W.*; Liu, Z., FeSe2-Decorated Bi2SeNanosheets for Chelator-Free 64Cu-labeling and Multimodal Image-Guided Photothermal-Radiation Therapy. Journal of Nuclear Medicine 2016,57.

42.  Cheng, L.*; Shen, S.; Shi, S.; Yi, Y.; Wang, X.; Song, G.; Yang, K.; Liu, G.; Barnhart, T. E.; Cai, W.*; Liu, Z.*, FeSe2-Decorated Bi2Se3 Nanosheets Fabricated via Cation Exchange for Chelator-Free Cu-64-Labeling and Multimodal Image-Guided Photothermal-Radiation Therapy. Advanced Functional Materials 2016,26 (13), 2185-2197.

43.  Cheng, L.*; Kamkaew, A.; Sun, H.; Jiang, D.; Valdovinos, H. F.; Gong, H.; England, C. G.; Goel, S.; Barnhart, T. E.; Cai, W.*, Dual-Modality Positron Emission Tomography/Optical Image-Guided Photodynamic Cancer Therapy with Chlorin e6-Containing Nanomicelles. ACS Nano 2016,10 (8), 7721-7730.

44.  Cheng, L.; Kamkaew, A.; Shen, S.; Valdovinos, H. F.; Sun, H.; Hernandez, R.; Goel, S.; Liu, T.; Thompson, C. R.; Barnhart, T. E.; Liu, Z.*; Cai, W.*, Facile Preparation of Multifunctional WS2/WOx Nanodots for Chelator-Free Zr-89-Labeling and In Vivo PET Imaging. Small 2016,12 (41), 5750-5758.

45.  Cheng, L.; Kamkaew, A.; Shen, S.; Valdovinos, H.; Barnhart, T.; Cai, W.*; Liu, Z., Chelator-Free 89Zr-labeling of Ultra-small WS2/WOx Quantum Dots for PET Imaging. Journal of Nuclear Medicine 2016,57.

46.  Chao, Y.; Wang, G.; Liang, C.; Yi, X.; Zhong, X.; Liu, J.; Gao, M.; Yang, K.*; Cheng, L.*; Liu, Z.*, Rhenium-188 Labeled Tungsten Disulfide Nanoflakes for Self-Sensitized, Near-Infrared Enhanced Radioisotope Therapy. Small 2016,12 (29), 3967-3975.

 

地址:江苏省苏州市仁爱路199号苏州大学910-408B

联系电话:0512-65880317

Email: lcheng2@suda.edu.cn


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